reg3a (P08570) Protein Card

General Information

Name	reg3a
Alternative name(s)	Reg12a
Organism	Conus regius
Organism region	Eastern Pacific
Organism diet	vermivorous
Protein Type	Wild type
Protein precursor	reg3a precursor (8571)

Classification

Conopeptide class	conotoxin
Gene superfamily	M superfamily
Cysteine framework	III
Pharmacological family

Sequence

GCCOOQWCGODCTSOCC
Modified residues	position symbol name 4 O 4-Hydroxyproline 5 O 4-Hydroxyproline 10 O 4-Hydroxyproline 15 O 4-Hydroxyproline
Sequence evidence	protein level
Average Mass	1814.97
Monoisotopic Mass	1813.50
Isoelectric Point	3.17
Extinction Coefficient [280nm]	5500.00

References

Franco,A., Pisarewicz,K., Moller,C., Mora,D., Fields,G.B. and Mari,F. (2006) Hyperhydroxylation: a new strategy for neuronal targeting by venomous marine molluscs Prog. Mol. Subcell. Biol. 43:83

Franco,A., Dovell,S., Möller,C., Grandal,M., Clark,E. and Marí,F. (2018) Structural plasticity of mini-M conotoxins - expression of all mini-M subtypes by Conus regius. FEBS J. 285:887-902

Internal links

Protein Precursor	reg3a precursor (8571)
Nucleic acids
Structure

External links

UniProtKB/Swiss-Prot	P85016
Ncbi	P85016

Tools

Please cite:
Kaas Q, Yu R, Jin AH, Dutertre S and Craik DJ. ConoServer: updated content, knowledge, and discovery tools in the conopeptide database. Nucleic Acids Research (2012) 40(Database issue):D325-30
Kaas Q, Westermann JC, Halai R, Wang CK and Craik DJ. ConoServer, a database for conopeptide sequences and structures. Bioinformatics (2008) 24(3):445-6

ConoServer is managed at the Institute of Molecular Bioscience IMB, Brisbane, Australia.

The database and computational tools found on this website may be used for academic research only, provided that it is referred to ConoServer, the database of conotoxins (http://www.conoserver.org) and the above reference is cited. For any other use please contact David Craik (d.craik@imb.uq.edu.au).

Contacts:
David Craik
Quentin Kaas

Last updated: Friday 29 September 2023