R11.18 (P00837) Protein Card

General Information

Name	R11.18
Organism	Conus radiatus
Organism region	Indo-Pacific
Organism diet	piscivorous
Protein Type	Wild type
Notes	One of the NCBI card states that this sequence is from the precursor (the mature peptide corresponds to this sequence but the last residue) while the other card states that the whole sequence is the mature peptide.

Classification

Conopeptide class	conotoxin
Gene superfamily	I1 superfamily
Cysteine framework	XI
Pharmacological family

Sequence

GAVPCGKDGRQCRNHADCCNCCPFGTCAPSTNRILPGCSTG MFlTR
Modified residues	position symbol name 44 l D-leucine
Sequence evidence	nucleic acid level
Average Mass	4812.48
Monoisotopic Mass	4809.02
Isoelectric Point	12.08
Extinction Coefficient [280nm]	NA

References

Jimenez,E.C., Shetty,R.P., Lirazan,M., Rivier,J., Walker,C., Abogadie,F.C., Yoshikami,D., Cruz,L.J. and Olivera,B.M. (2003) Novel excitatory Conus peptides define a new conotoxin superfamily J. Neurochem. 85:610-621

Internal links

Nucleic acids	Conus radiatus I-superfamily conotoxin R11.18 (R11.18) mRNA, partial cds
Structure

External links

UniProtKB/Swiss-Prot	Q7Z097
Ncbi	Q7Z097, AAP41538

Tools

Please cite:
Kaas Q, Yu R, Jin AH, Dutertre S and Craik DJ. ConoServer: updated content, knowledge, and discovery tools in the conopeptide database. Nucleic Acids Research (2012) 40(Database issue):D325-30
Kaas Q, Westermann JC, Halai R, Wang CK and Craik DJ. ConoServer, a database for conopeptide sequences and structures. Bioinformatics (2008) 24(3):445-6

ConoServer is managed at the Institute of Molecular Bioscience IMB, Brisbane, Australia.

The database and computational tools found on this website may be used for academic research only, provided that it is referred to ConoServer, the database of conotoxins (http://www.conoserver.org) and the above reference is cited. For any other use please contact David Craik (d.craik@imb.uq.edu.au).

Contacts:
David Craik
Quentin Kaas

Last updated: Tuesday 26 September 2023