Fr3.1 (P07899) Protein Card

General Information

Name	Fr3.1 (named by ConoServer)
Alternative name(s)	Fr2091
Organism	Conus frigidus
Protein Type	Wild type
Protein precursor	Fr3.1 precursor (7896)
Notes	MS results showed that Fr2048 has multiple post-translational modifications, including Fr2064 (P → O), Fr2108(E → γ, P → O) and Fr2091 (E → γ, P → O, Q → Z).

Classification

Conopeptide class	conotoxin
Gene superfamily	M superfamily
Cysteine framework	III
Pharmacological family

Sequence

ZQ(Gla)CCDODWCDGACYNCC
Modified residues	position symbol name 1 Z Pyroglutamic acid 3 Gla Gamma carboxylic glutamic acid 7 O 4-Hydroxyproline
Sequence evidence	protein level
Average Mass	2093.14
Monoisotopic Mass	2091.51
Isoelectric Point	NA
Extinction Coefficient [280nm]	NA

References

Vijayasarathy, M., Basheer, S.M. and Balaram, P. (2018) Cone Snail Glutaminyl Cyclase Sequences from Transcriptomic Analysis and Mass Spectrometric Characterization of Two Pyroglutamyl Conotoxins Journal of proteome research 17:2695-2703

Internal links

Protein Precursor	Fr3.1 precursor (7896)
Nucleic acids
Structure

External links

Tools

Please cite:
Kaas Q, Yu R, Jin AH, Dutertre S and Craik DJ. ConoServer: updated content, knowledge, and discovery tools in the conopeptide database. Nucleic Acids Research (2012) 40(Database issue):D325-30
Kaas Q, Westermann JC, Halai R, Wang CK and Craik DJ. ConoServer, a database for conopeptide sequences and structures. Bioinformatics (2008) 24(3):445-6

ConoServer is managed at the Institute of Molecular Bioscience IMB, Brisbane, Australia.

The database and computational tools found on this website may be used for academic research only, provided that it is referred to ConoServer, the database of conotoxins (http://www.conoserver.org) and the above reference is cited. For any other use please contact David Craik (d.craik@imb.uq.edu.au).

Contacts:
David Craik
Quentin Kaas

Last updated: Saturday 23 September 2023