Mi27.2 precursor (P06722) Protein Card

General Information
Name Mi27.2 precursor (named by ConoServer)
Alternative name(s) Mil046 precursor
Organism Conus miles
Organism region Indo-Pacific
Organism diet vermivorous
Protein Type Precursor

Classification
Conopeptide class conotoxin
Gene superfamily G2 superfamily
Cysteine framework XXVII
Pharmacological family

Sequence
MRFFFLLLTVALFLTSITGDDA
ERMLGMKEGGYVR
EDCGSD
CAPCGGECCCEPNSCIDGTCHHESSPN
Sequence evidence nucleic acid level
Sequence region
[1-22]signal sequence
[36-68]mature peptideMi27.2

References
Jin,A.H., Dutertre,S., Kaas,Q., Lavergne,V., Kubala,P. and Alewood,P.F. (2013) Transcriptomic messiness in the venom duct of Conus miles contributes to conotoxin diversity. Mol. Cell Proteomics 12:3824-3833
Jin, A.H., Dekan, Z., Smout, M.J., Wilson, D., Dutertre, S., Vetter, I., Lewis, R.J., Loukas, A., Daly, N.L. and Alewood, P.F. (2017) Conotoxin Φ‐MiXXVIIA from the Superfamily G2 Employs a Novel Cysteine Framework that Mimics Granulin and Displays Anti‐Apoptotic Activity Angewandte Chemie International Edition 56:14973-14976

Internal links
Nucleic acids Conus miles conopeptide Mi046 mRNA, complete cds.
Structure

External links
Ncbi AKB91384

Tools