MiXXVIIA precursor (P06721) Protein Card

General Information

Name	MiXXVIIA precursor
Alternative name(s)	Mi045 precursor,Ф-MiXXVIIA precursor
Organism	Conus miles
Organism region	Indo-Pacific
Organism diet	vermivorous
Protein Type	Precursor

Classification

Conopeptide class	conotoxin
Gene superfamily	G2 superfamily
Cysteine framework	XXVII
Pharmacological family

Sequence

MRFFFLLLTVALFLTSITGDDA ERMLGMKEGGYVR EDCGSD CMPCGGECCCEPNSCIDGTCHHESSPN
Sequence region	[1-22] signal sequence [36-68] mature peptide MiXXVIIA

References

Jin,A.H., Dutertre,S., Kaas,Q., Lavergne,V., Kubala,P. and Alewood,P.F. (2013) Transcriptomic messiness in the venom duct of Conus miles contributes to conotoxin diversity. Mol. Cell Proteomics 12:3824-3833

Jin, A.H., Dekan, Z., Smout, M.J., Wilson, D., Dutertre, S., Vetter, I., Lewis, R.J., Loukas, A., Daly, N.L. and Alewood, P.F. (2017) Conotoxin Φ‐MiXXVIIA from the Superfamily G2 Employs a Novel Cysteine Framework that Mimics Granulin and Displays Anti‐Apoptotic Activity Angewandte Chemie International Edition 56:14973-14976

Internal links

Nucleic acids	Conus miles conopeptide Mi045 mRNA, complete cds.
Structure

External links

Ncbi

AKB91383

Tools

Please cite:
Kaas Q, Yu R, Jin AH, Dutertre S and Craik DJ. ConoServer: updated content, knowledge, and discovery tools in the conopeptide database. Nucleic Acids Research (2012) 40(Database issue):D325-30
Kaas Q, Westermann JC, Halai R, Wang CK and Craik DJ. ConoServer, a database for conopeptide sequences and structures. Bioinformatics (2008) 24(3):445-6

ConoServer is managed at the Institute of Molecular Bioscience IMB, Brisbane, Australia.

The database and computational tools found on this website may be used for academic research only, provided that it is referred to ConoServer, the database of conotoxins (http://www.conoserver.org) and the above reference is cited. For any other use please contact David Craik (d.craik@imb.uq.edu.au).

Contacts:
David Craik
Quentin Kaas

Last updated: Tuesday 30 May 2023