Cal14.12 (P06669) Protein Card

General Information

Name	Cal14.12
Organism	Conus californicus
Organism region	Eastern Pacific
Organism diet	piscivorous
Protein Type	Wild type
Protein precursor	Cal14.12 precursor (4014)
Notes	The peptide was predicted from the precursor protein sequence using potential cleavage after lysine residues. None of the usual cleavage pattern was otherwise found.

Classification

Conopeptide class	conotoxin
Gene superfamily	Divergent MKVAVVLLVS
Cysteine framework	XIV
Pharmacological family

Sequence

AACKAACKKGAKLILKAAAPLASQVCGPACNAALA
Sequence evidence	nucleic acid level
Average Mass	3294.01
Monoisotopic Mass	3291.74
Isoelectric Point	11.71
Extinction Coefficient [280nm]	NA

References

Biggs,J.S., Watkins,M., Puillandre,N., Ownby,J.P., Lopez-Vera,E., Christensen,S., Moreno,K.J., Bernaldez,J., Licea-Navarro,A. and Olivera,B.M. (2010) Evolution of Conus peptide toxins: analysis of Conus californicus Reeve, 1844. Mol. Phylogenet. Evol. 56:1-12

Internal links

Protein Precursor	Cal14.12 precursor (4014)
Nucleic acids
Structure

External links

Tools

Please cite:
Kaas Q, Yu R, Jin AH, Dutertre S and Craik DJ. ConoServer: updated content, knowledge, and discovery tools in the conopeptide database. Nucleic Acids Research (2012) 40(Database issue):D325-30
Kaas Q, Westermann JC, Halai R, Wang CK and Craik DJ. ConoServer, a database for conopeptide sequences and structures. Bioinformatics (2008) 24(3):445-6

ConoServer is managed at the Institute of Molecular Bioscience IMB, Brisbane, Australia.

The database and computational tools found on this website may be used for academic research only, provided that it is referred to ConoServer, the database of conotoxins (http://www.conoserver.org) and the above reference is cited. For any other use please contact David Craik (d.craik@imb.uq.edu.au).

Contacts:
David Craik
Quentin Kaas

Last updated: Friday 29 September 2023