Mr15.2 (P05489) Protein Card

General Information

Name	Mr15.2
Alternative name(s)	Mr094
Organism	Conus marmoreus
Organism region	Indo-Pacific
Organism diet	molluscivorous
Protein Type	Wild type
Protein precursor	Mr15.2 precursor (5488)
Notes	The sequence was only partly confirmed by MS/MS but the peptide mass was found by MS (Dutertre 2013).

Classification

Conopeptide class	conotoxin
Gene superfamily	N superfamily
Cysteine framework	XV
Pharmacological family

Sequence

CRSGKTCORVGODVCC(Gla)RSDCFCKLVOARPFWRYRCI CL
Modified residues	position symbol name 8 O 4-Hydroxyproline 12 O 4-Hydroxyproline 17 Gla Gamma carboxylic glutamic acid 27 O 4-Hydroxyproline
Sequence evidence	protein level
Average Mass	4609.36
Monoisotopic Mass	4606.03
Isoelectric Point	12.25
Extinction Coefficient [280nm]	6990.00

References

Dutertre,S., Jin,A.H., Kaas,Q., Jones,A., Alewood,P.F. and Lewis,R.J. (2013) Deep venomics reveals the mechanism for expanded peptide diversity in cone snail venom. Mol. Cell Proteomics 12:312-329

Internal links

Protein Precursor	Mr15.2 precursor (5488)
Nucleic acids
Structure

External links

Tools

Please cite:
Kaas Q, Yu R, Jin AH, Dutertre S and Craik DJ. ConoServer: updated content, knowledge, and discovery tools in the conopeptide database. Nucleic Acids Research (2012) 40(Database issue):D325-30
Kaas Q, Westermann JC, Halai R, Wang CK and Craik DJ. ConoServer, a database for conopeptide sequences and structures. Bioinformatics (2008) 24(3):445-6

ConoServer is managed at the Institute of Molecular Bioscience IMB, Brisbane, Australia.

The database and computational tools found on this website may be used for academic research only, provided that it is referred to ConoServer, the database of conotoxins (http://www.conoserver.org) and the above reference is cited. For any other use please contact David Craik (d.craik@imb.uq.edu.au).

Contacts:
David Craik
Quentin Kaas

Last updated: Wednesday 27 September 2023