Cal14.2b (P04161) Protein Card

General Information
Name Cal14.2b
Organism Conus californicus
Organism region Eastern Pacific
Organism diet piscivorous
Protein Type Wild type
Protein precursor Cal14.2b precursor (4018)
Notes

Predicted by ConoServer from protein precursor.

Synthetic cal14.2b shows the potential therapeutic use in endocrinal pathologies, for example Type 2 Diabetes (Lugo-Fabres et al., 2021).

Classification
Conopeptide class conotoxin
Gene superfamily L superfamily
Cysteine framework XIV
Pharmacological family

Sequence
ECPPRCPTSHCNAGTC
Sequence evidence nucleic acid level
Average Mass 1671.85
Monoisotopic Mass 1670.61
Isoelectric Point 8.31
Extinction Coefficient [280nm] -1.00

References
Biggs,J.S., Watkins,M., Puillandre,N., Ownby,J.P., Lopez-Vera,E., Christensen,S., Moreno,K.J., Bernaldez,J., Licea-Navarro,A. and Olivera,B.M. (2010) Evolution of Conus peptide toxins: analysis of Conus californicus Reeve, 1844. Mol. Phylogenet. Evol. 56:1-12
Lugo-Fabres,P.H., Otero-Sastre,L.M., Bernáldez-Sarabia,J., Camacho-Villegas,T.A., Sánchez-Campos,N., Serrano-Bello,J., Medina,L.A., Muñiz-Hernández,S., de la Cruz,L., Arenas,I., Barajas-Martínez,A., Garcia,D.E., Nuñez-Garcia,L., González-Canudas,J. and Licea-Navarro,A.F. (2021) Potential Therapeutic Applications of Synthetic Conotoxin s-cal14.2b, Derived from Californiconus californicus, for Treating Type 2 Diabetes Biomedicines 9

Internal links
Protein Precursor Cal14.2b precursor (4018)
Nucleic acids
Structure

External links

Tools