ImI [C2Agl,C8Agl] (P03636) Protein Card

General Information

Name	ImI [C2Agl,C8Agl]
Organism	synthetic construct
Protein Type	Synthetic
Parent	ImI

Classification

Conopeptide class	conotoxin
Gene superfamily
Pharmacological family

Sequence

G(Agl)CSDPR(Agl)AWRC(nh2)
Modified residues	position symbol name 2 Agl Carbabridge [C2 alkene] (half) 8 Agl Carbabridge [C2 alkene] (half) 13 nh2 C-term amidation
Average Mass	1343.54
Monoisotopic Mass	1342.60
Isoelectric Point	10.99
Extinction Coefficient [280nm]	5500.00

References

MacRaild,C.A., Illesinghe,J., van Lierop,B.J., Townsend,A.L., Chebib,M., Livett,B.G., Robinson,A.J. and Norton,R.S. (2009) Structure and activity of (2,8)-dicarba-(3,12)-cystino alpha-ImI, an alpha-conotoxin containing a nonreducible cystine analogue. J. Med. Chem. 52:755-762

Internal links

Nucleic acids
Structure	Solution structure of dicarba-ImI: an alpha-conotoxin with a non-reducible cystine analogue

External links

Tools

Please cite:
Kaas Q, Yu R, Jin AH, Dutertre S and Craik DJ. ConoServer: updated content, knowledge, and discovery tools in the conopeptide database. Nucleic Acids Research (2012) 40(Database issue):D325-30
Kaas Q, Westermann JC, Halai R, Wang CK and Craik DJ. ConoServer, a database for conopeptide sequences and structures. Bioinformatics (2008) 24(3):445-6

ConoServer is managed at the Institute of Molecular Bioscience IMB, Brisbane, Australia.

The database and computational tools found on this website may be used for academic research only, provided that it is referred to ConoServer, the database of conotoxins (http://www.conoserver.org) and the above reference is cited. For any other use please contact David Craik (d.craik@imb.uq.edu.au).

Contacts:
David Craik
Quentin Kaas

Last updated: Wednesday 27 September 2023