SrXIA (P02802) Protein Card

General Information

Name	SrXIA
Alternative name(s)	Sr11.1,Sr11a
Organism	Conus spurius
Organism region	Western Atlantic and Caribbean
Organism diet	vermivorous
Protein Type	Wild type
Protein precursor	SrXIA precursor (3895)
Notes	Produced stiffening of body, limbs and tail when injected intracranially into mice.

Classification

Conopeptide class	conotoxin
Gene superfamily	I2 superfamily
Cysteine framework	XI
Pharmacological family

Sequence

CRTEGMSC(Gla)(Gla)NQQCCWRSCCRGECEAPCRFGP(nh2)
Modified residues	position symbol name 9 Gla Gamma carboxylic glutamic acid 10 Gla Gamma carboxylic glutamic acid 33 nh2 C-term amidation
Sequence evidence	protein level
Average Mass	3739.08
Monoisotopic Mass	3736.30
Isoelectric Point	4.80
Extinction Coefficient [280nm]	5500.00

References

Aguilar,M.B., López-Vera,E., Heimer de la Cotera,E.P., Falcón,A., Olivera,B.M. and Maillo,M. (2007) I-conotoxins in vermivorous species of the West Atlantic: peptide sr11a from Conus spurius. Peptides 28:18-23

Internal links

Protein Precursor	SrXIA precursor (3895)
Nucleic acids
Structure

External links

UniProtKB/Swiss-Prot	P0C615
Ncbi	P0C615

Tools

Please cite:
Kaas Q, Yu R, Jin AH, Dutertre S and Craik DJ. ConoServer: updated content, knowledge, and discovery tools in the conopeptide database. Nucleic Acids Research (2012) 40(Database issue):D325-30
Kaas Q, Westermann JC, Halai R, Wang CK and Craik DJ. ConoServer, a database for conopeptide sequences and structures. Bioinformatics (2008) 24(3):445-6

ConoServer is managed at the Institute of Molecular Bioscience IMB, Brisbane, Australia.

The database and computational tools found on this website may be used for academic research only, provided that it is referred to ConoServer, the database of conotoxins (http://www.conoserver.org) and the above reference is cited. For any other use please contact David Craik (d.craik@imb.uq.edu.au).

Contacts:
David Craik
Quentin Kaas

Last updated: Monday 11 December 2023