Fe14.2 (P02720) Protein Card

General Information

Name	Fe14.2
Organism	Conus ferrugineus
Organism region	Indo-Pacific
Organism diet	vermivorous
Protein Type	Wild type
Protein precursor	Fe14.2 precursor (1187)

Classification

Conopeptide class	conotoxin
Gene superfamily	J superfamily
Cysteine framework	XIV
Pharmacological family

Sequence

SSGSTVCKMMCRLGYGHLYPSCGCR(nh2)
Modified residues	position symbol name 26 nh2 C-term amidation
Sequence evidence	nucleic acid level
Average Mass	2692.17
Monoisotopic Mass	2690.15
Isoelectric Point	10.64
Extinction Coefficient [280nm]	2980.00

References

Imperial,J.S., Bansal,P.S., Alewood,P.F., Daly,N.L., Craik,D.J., Sporning,A., Terlau,H., Lopez-Vera,E., Bandyopadhyay,P.K. and Olivera,B.M. (2006) A novel conotoxin inhibitor of Kv1.6 channel and nAChR subtypes defines a new superfamily of conotoxins Biochemistry 45:8331-8340

Internal links

Protein Precursor	Fe14.2 precursor (1187)
Nucleic acids
Structure

External links

Ncbi	Q0N4U3, ABE27011

Tools

Please cite:
Kaas Q, Yu R, Jin AH, Dutertre S and Craik DJ. ConoServer: updated content, knowledge, and discovery tools in the conopeptide database. Nucleic Acids Research (2012) 40(Database issue):D325-30
Kaas Q, Westermann JC, Halai R, Wang CK and Craik DJ. ConoServer, a database for conopeptide sequences and structures. Bioinformatics (2008) 24(3):445-6

ConoServer is managed at the Institute of Molecular Bioscience IMB, Brisbane, Australia.

The database and computational tools found on this website may be used for academic research only, provided that it is referred to ConoServer, the database of conotoxins (http://www.conoserver.org) and the above reference is cited. For any other use please contact David Craik (d.craik@imb.uq.edu.au).

Contacts:
David Craik
Quentin Kaas

Last updated: Thursday 28 September 2023