Mr3.8 (P02689) Protein Card

General Information

Name	Mr3.8
Alternative name(s)	Mr044
Organism	Conus marmoreus
Organism region	Indo-Pacific
Organism diet	molluscivorous
Protein Type	Wild type
Protein precursor	Mr3.8 precursor (1082) Mr3.8 precursor (6168) Mr3.8 precursor (6194) Mr3.8 precursor (6195) Mr3.8 precursor (6197) Mr3.8 precursor (6198) Mr3.8 precursor (6212) Mr3.8 precursor (6213) Mr3.8 precursor (6214) Mr3.8 precursor (6215) Mr3.8 precursor (6216) Mr3.8 precursor (6217) Mr3.8 precursor (6218) Mr3.8 precursor (6219) Mr3.8 precursor (6220) Mr3.8 precursor (6221)

Classification

Conopeptide class	conotoxin
Gene superfamily	M superfamily
Cysteine framework	III
Pharmacological family

Sequence

CCHWNWCDHLCSCCGS
Sequence evidence	protein level
Average Mass	1851.05
Monoisotopic Mass	1849.53
Isoelectric Point	6.81
Extinction Coefficient [280nm]	11000.00

References

Han,Y.H., Wang,Q., Jiang,H., Liu,L., Xiao,C., Yuan,D.D., Shao,X.X., Dai,Q.Y., Cheng,J.S. and Chi,C.W. (2006) Characterization of novel M-superfamily conotoxins with new disulfide linkage FEBS J. 273:4972-4982

Wang,Q., Jiang,H., Han,Y.H., Yuan,D.D. and Chi,C.W. (2008) Two different groups of signal sequence in M-superfamily conotoxins. Toxicon 51:813-822

Dutertre,S., Jin,A.H., Kaas,Q., Jones,A., Alewood,P.F. and Lewis,R.J. (2013) Deep venomics reveals the mechanism for expanded peptide diversity in cone snail venom. Mol. Cell Proteomics 12:312-329

Internal links

Protein Precursor	Mr3.8 precursor (1082) Mr3.8 precursor (6168) Mr3.8 precursor (6194) Mr3.8 precursor (6195) Mr3.8 precursor (6197) Mr3.8 precursor (6198) Mr3.8 precursor (6212) Mr3.8 precursor (6213) Mr3.8 precursor (6214) Mr3.8 precursor (6215) Mr3.8 precursor (6216) Mr3.8 precursor (6217) Mr3.8 precursor (6218) Mr3.8 precursor (6219) Mr3.8 precursor (6220) Mr3.8 precursor (6221)
Nucleic acids
Structure

External links

Ncbi	Q5EHP2, AAW78561

Tools

Please cite:
Kaas Q, Yu R, Jin AH, Dutertre S and Craik DJ. ConoServer: updated content, knowledge, and discovery tools in the conopeptide database. Nucleic Acids Research (2012) 40(Database issue):D325-30
Kaas Q, Westermann JC, Halai R, Wang CK and Craik DJ. ConoServer, a database for conopeptide sequences and structures. Bioinformatics (2008) 24(3):445-6

ConoServer is managed at the Institute of Molecular Bioscience IMB, Brisbane, Australia.

The database and computational tools found on this website may be used for academic research only, provided that it is referred to ConoServer, the database of conotoxins (http://www.conoserver.org) and the above reference is cited. For any other use please contact David Craik (d.craik@imb.uq.edu.au).

Contacts:
David Craik
Quentin Kaas

Last updated: Thursday 28 September 2023