BtIIIA (P01516) Protein Card

General Information

Name	BtIIIA
Alternative name(s)	BeTXIa
Organism	Conus betulinus
Organism region	Indo-Pacific
Organism diet	vermivorous
Protein Type	Wild type

Classification

Conopeptide class	conotoxin
Gene superfamily	M superfamily
Cysteine framework	III
Pharmacological family

Sequence

CCKQSCTTCMPCCW
Sequence evidence	protein level
Average Mass	1590.90
Monoisotopic Mass	1589.47
Isoelectric Point	10.95
Extinction Coefficient [280nm]	5500.00

References

Chen,J.S., Fan,C.X., Hu,K.P., Wei,K.H. and Zhong,M.N. (1999) Studies on conotoxins of Conus betulinus J Nat Toxins 8:341-349

Akcan,M., Cao,Y., Chongxu,F. and Craik,D.J. (2013) The three-dimensional solution structure of mini-M conotoxin BtIIIA reveals a disconnection between disulfide connectivity and peptide fold. Bioorg. Med. Chem. 21:3590-3596

Internal links

Nucleic acids
Structure	BtIIIA NMR solution structure

External links

UniProtKB/Swiss-Prot	P58623
Ncbi	P58623

Tools

Please cite:
Kaas Q, Yu R, Jin AH, Dutertre S and Craik DJ. ConoServer: updated content, knowledge, and discovery tools in the conopeptide database. Nucleic Acids Research (2012) 40(Database issue):D325-30
Kaas Q, Westermann JC, Halai R, Wang CK and Craik DJ. ConoServer, a database for conopeptide sequences and structures. Bioinformatics (2008) 24(3):445-6

ConoServer is managed at the Institute of Molecular Bioscience IMB, Brisbane, Australia.

The database and computational tools found on this website may be used for academic research only, provided that it is referred to ConoServer, the database of conotoxins (http://www.conoserver.org) and the above reference is cited. For any other use please contact David Craik (d.craik@imb.uq.edu.au).

Contacts:
David Craik
Quentin Kaas

Last updated: Sunday 24 September 2023